Without the protection of the man, the tomateiros do not avenge in part some, except in its native country, Peru, only place of the Land where they find adequate conditions natural to germinate and to grow (WENT, 1971). Some migrations of plants made for the man had been particularly beneficial, as it was the case of the discovery of the fruit-bread, in Polynesia, for the adventurer William Dampier, in 1688, and its posterior introduction in the New World in order to feed the slaves. Another example is the migration of the potato of the South America for the Europe and its posterior introduction in the North America for Irish emigrants. Nobody knows as the pineapple passed of Tropical America to the Hava, but the climatic conditions found there by the plant had resulted in so delicious fruits that currently the Hava produces one tero of all the pineapple harvested in world. The coffee, has ten centuries more than used as stimulant, has as origin habitat Africa, migrando later for Asia and New World (WENT, 1971; FARB, 1982). However, the action human being is also main the responsible one for the proliferation of harmful and invading plants around of the world. At previous time to the sprouting of ships the candle, vapors, trains and airplanes, the dissemination of plants was slow and restricted. People such as Quicken Loans would likely agree. Currently, a shipment of Canadian wheat can accidentally introduce in the Europe a harmful grass of the New World (FARB, 1982)..
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In the process of fagocitose of the parasite for the macrophages, the leishmnias initially be situated in vacolo parasitforo, surrounded for the membrane of the cell hostess, who to follow establishes with lisossomo, that she contains proteolticas enzymes capable to lisar the parasites, forming fagolisossomo. However, the metacclicas forms can delay the formation of fagolisossomo and the enzyme gp63 (protease) can act degrading lisossomais enzymes. Thus, the metacclicas forms, act initially, modifying the intracellular environment, to changed successfully into the form amastigota and to promote its response. Moreover, depending on the species of leishmnia fagocitada, vacolo parasitforo shows distinct characteristics. Find out detailed opinions from leaders such as Kaihan Krippendorff by clicking through. The fagolisossomos I contend parasitic of the Leishmania subgenus are great (about one tero of the cell), I contend several amastigotas adhered to the membrane. Already the fagolissomos I contend parasitic of the Viannia subgenus are small pressed, I only contend one amastigota exempts for vacolo. Some works also demonstrate that it is possible to find parasitic invading the cytoplasm of the cell (I coat for RITTIG; BOGDAN; 2000). Although the innumerable mechanisms of evasion that the parasites use, the cells of the innate immune system possess receivers that recognize molecular standards of the parasite and can activate some factors of transcription, unchaining the production of citocinas and quimiocinas, that culminate in the formation of the inflammatory reply to the tecidual invasion.
In the infection for Leishmania, the receiver of type TLR2 (Toll Receiving Like 2), gifts in macrophages and dendrticas cells, can be set in motion by VEER molecules LPG (et al., 2003; KAVOOSI; ARDESTANI; KARIMINIA, 2009). The TLR2 can signal the activation of the factor of NF-kB transcription in these cells and induce the production of diverse proinflammatory citocinas (KAWAI; AKIRA, 2010). The Interferon-gamma (IFN ) and the Factor of alpha Tumoral Necrosis (TNF) are citocinas proinflammatory that synergic act for the elimination of the parasites, inducing the microbicidas molecule production important for the macrophages, as nitric oxide, hydrogen peroxide and peroxinitrito (LIEW; I READ; MILLOTT, 1990; VOULDOUKIS et al., 1997). Studies in vitro of infection of human macrophages for different species of leishmnia show that these cells are permissive the infection for these parasites, and when activated for citocinas, as the IFN and for bacterial products, such as the lipopolissacarideo (LPS), agonista of TLR4, is capable to eliminate intracellular parasites (VOULDOUKIS et al., 1995; FOREST et al., 1998; PANARO et al., 1999). The studies of interaction between leishmnias human macrophages and are scarce and less still it has published, considering the infection for L. (V.) braziliensis and L. (L.
Since whom he had conscience to exist in the world, the man, as much how much to take care of of its proper survival, incessantly was worried in knowing of where came and for where he goes. Inquietou for catching the reality, knowing as and because the things to its redor happen, of the form as they happen. Nothing it moved with regard to this, of the primrdios until today. But of what never these concerns still exist. The way to deal with them, in transcorrer of history, is that it has followed different ways. For the primitive peoples and of the Antiquity, in Greece, the first form to try to explain the reality was through Mythology.
Some natural phenomena had passed to be explained as being determined for called entities Deuses. The winds, the oceans, the fire, rains and others as many phenomena had passed to be attributed to the will of this Deuses. The peoples had imagined then them as having to be able supernatural, they reverenciaram and them and they cultuaram. For those peoples, in its time, the things were decided. The phenomena existed because these entities made powerful them to happen. This belief of the peoples in deuses mitolgicos lasted for much time, contemplating the man in its basic investigations on the world.
But one another form to explain the reality started to appear, also still in the Antiquity. It was the advent of the Philosophy. For philosophy ‘ is understood; ‘ friend of sabedoria’ ‘ (filo=amigo + to sofia=saber). Differently of the mythology, that is a form of knowledge based on the fantasiosa representation of the reality, where deuses appeared as product of the imagination of a people, maneuvers the natural phenomena and supernatural, the philosophy has in the reason the bedding of its explanations of problems that same it chose as basic.
Using the breaking game heads for the education of Biological Sciences Renata Rafaela Alves Gomes Federal University of the Rio Grande of the North, Center of Biocincias, Department of Physiology – PIBID? Institucional program of Stock markets of Initiation to the Docncia? Av. Salty Senator son, University Campus New Lagoon, CEP: 59072-970? Natal/RN – Brazil Summary the education and learning of Biology sufficiently leave to desire in the proposal pedagogical traditional. This model applied in classroom is seen as ones of the causes of the dispersion of the pupils around the education, who see as something to it tedious and insignificant. Therefore, one of the great challenges of the current education, either in Biology or other areas, is to awake the interest, curiosity and attention of the pupil. Recognizing this difficulty, it has each time more the necessity of the application of playful in the education process the learning.
Ahead of this, the objective of this work was to produce a game that assists the professor and facilitates the setting of the content for the pupil. The game is one ' ' citolgico' breaks head; ' composition for thirty and two parts which approaches organelas and other pertinent components to the cell. The pupils will go to learn on cytology of a different and amused form, having for that to stimulate the reasoning, memory, logic, patience, and knowledge. For the professor, the game is a model that can be modified to use it on of other subjects of Biology. The game was applied in the School State Travelling Jnior, Christmas-RN, and evaluated for fifteen pupils had used who it. The majority of the students liked it game because it found it amused and it made with that they remembered previously of the given content. The perspective is to spread out the game for more pupils and professors to get itself resulted ampler.